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IMULAN’s Stomatitis Immunotherapeutic Shows Promise

14 years ago

23rd June, 2010 00h00

Imulan BioTherapeutics, LLC (IMULAN) announced encouraging early results from clinical trials on their T-Cell Receptor (TCR) therapeutic vaccine for feline stomatitis. Feline stomatitis, also referred to as gingivostomatitis, is an immune mediated inflammatory condition affecting the oral cavity. The TCR therapeutic vaccine is an immune modulating biologic that re-programs specific immune cells (T-cells) implicated in feline stomatitis. IMULAN’s TCR therapeutic vaccine is currently being evaluated in a multi center, double blind clinical efficacy study in cats with stomatitis. Dr. Daniel Gingerich, IMULAN’s Chief Scientific Officer stated, “Although specifics of the clinical findings are not being released, interim analysis of data from case reports received thus far are very encouraging. The interim data are an internal milestone to allocate our resources towards focusing on our TCR vaccine program, designed to qualify for regulatory approval for feline stomatitis.” About the TCR peptides: T-Cell Receptor peptides are immune modulating biologics designed to restore immune function and normalize cytokine profiles by precisely regulating T-helper cell activity. The peptides are undergoing formal approval process for atopic dermatitis and feline stomatitis but have also evidenced promise for viral infections, cardiac disease, and fungal infections. T-Cell receptors are the gateway to the immune system, and are responsible for recognizing substances such as peptides. Once a T-cell receptor is activated, it triggers a cascade of cellular events that produce a systemic immune response. About IMULAN Imulan develops unique, precision immune regulating compounds for veterinary medicine. IMULAN’s primary focus is on biological strategies to treat infectious, autoimmune, and immune mediated diseases in small and large animal medicine. For more information about Imulan, please visit

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