New F(ab’)2 Rattlesnake Antivenom Efficacy Study Completed

BioVeteria Life Sciences, LLC (BioVeteria) announced the completion of a multi-center canine efficacy and safety study using a new F(ab’)2 antivenom for pit vipers (rattlesnakes, copperhead, cottonmouth). The study evaluated dogs envenomated by a variety of pit vipers in various geographical regions. Results showed that F(ab’)2 pit viper antivenom administration resulted in rapid and significant improvement in clinical scores and recovery of platelet values and clotting function. The study also had no reported adverse events from the use of the F(ab’)2 antivenom. Results from the study, entitled “Evaluation of an Antivenom F(ab’)2 in 74 Dogs Envenomated by North American Pit Vipers”, were presented at the International Veterinary Emergency and Critical Care Society’s 2010 annual conference and are being prepared for publication in a peer reviewed veterinary journal. BioVeteria’s polyvalent F(ab’)2 antivenom consists of antibody fragments previously shown to cross neutralize the venoms from all common North American pit vipers. The antivenom has been previously shown to cross neutralize venom from Mojave Venom A population, which snakes produce a potent neurotoxin called “Mojave toxin”. BioVeteria is also considering the development of several other antivenoms for veterinary medicine, including those for scorpions, black widows, and coral snakes. About BioVeteria Life Sciences, LLC BioVeteria is a privately held bioscience company that is developing a range of new products for veterinary medicine, including F(ab’)2 antivenoms, optimized nutraceuticals, diagnostics and devices for veterinary applications. Located in Prescott, AZ, BioVeteria is dedicated to advancing clinically meaningful technology for dogs, cats, and horses.

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