VRCC Canine Melanoma Vaccine First
17 years ago
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Posted
20th February, 2009 00h00
Dr Susan North and Luke at VRCC - the first patient in the UK to receive the Canine Melanoma Vaccine
Most oral tumours are not noticed early by owners so many go undiagnosed and untreated until they are advanced and the dog has a poor chance of recovery. However, Veterinary Surgeons can detect tumours of the mouth during routine oral examination.
Canine melanoma is an aggressive neoplasm treated with surgery and/or radiation therapy, which readily metastasises to the lymph nodes, liver, lungs and kidneys but is chemo-resistant and with little evidence that chemotherapy improves survival time.
The Canine Melanoma Vaccine develops effective immunotherapy in dogs that recognises and targets specific antigens on melanoma cells and may account for long-term tumour control and survival.
The vaccine is indicated for dogs with stage II or stage III oral melanoma and for which local disease control has been achieved, negative local lymph nodes or positive lymph nodes that were surgically removed or irradiated.
The conditional license was granted based on the reasonable expectation that when used along with surgery and/or radiation therapy to treat the initial tumour the vaccine may help extend survival time and improve quality of life in dogs with canine oral melanoma.
Prolonged survival time
US research concluded that canine patients with advanced disease have a median survival time of less than 5 months with standard therapies. In initial trials, dogs receiving the vaccination sequence had a median survival time of 389 days.
A canine Transdermal Device is especially matched to the Vaccine for needle –free delivery and optimal distribution. Veterinary Surgeons with a patient with oral melanoma should contact Dr Susan North at VRCC, www.vrcc.co.uk to discuss the case at an early stage, as initial treatment is important to ensure suitability for the Vaccine.
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